Immune Checkpoint Inhibitors Market Size, Trends, Share, Growth Analysis Report, COVID-19 Impact & Forecast
Immune checkpoint inhibitors are a type of
immunotherapy drug. Although traditional chemotherapeutic drugs are still the
first-line treatment option for most cancer types, targeted immune therapies
are becoming standard treatments for advanced-stage cancers. These drugs target
cell surface checkpoint proteins to stimulate the immune system's recognition
and destruction of cancer cells.
The global
immune checkpoint inhibitors market is growing due to an increase in
cancer prevalence across geographies and increased awareness of immune
checkpoint inhibitors. Furthermore, technological advancements in cancer
screening procedures, increased healthcare expenditures, an increase in
government initiatives to alleviate cancer, and an increase in public awareness
is expected to drive market growth.
The human body's immune system is dependent on
multiple checkpoints or immunological breaks that prevent the over-activation
of healthy cells or the immune system. Tumor or cancerous cells frequently use
these checkpoints to avoid detection and fight the immune system. To combat
such cancer cells, scientists and drug developers are increasingly turning to
immunotherapeutics, which use the body's own immune system or its components to
fight cancer. Although targeted-based therapeutics such as conjugated and
monoclonal antibodies have yielded promising results, there has been a surge of
interest in other classes of immunotherapeutics to treat and manage cancer,
such as immune checkpoint inhibitors, whole cell-based therapies, and
therapeutic cancer vaccines.
Because of the global increase in lung cancer
prevalence, the lung cancer segment currently dominates the market and is
expected to remain dominant during the forecast period. The increased use of
immune checkpoint inhibitors in the treatment of non-small cell lung cancer
(NSCLC) also contributes to the growth of this segment. Furthermore, an
increase in the geriatric population, an increase in the cigarette smoking
population, and advancements in lung cancer diagnostic techniques all
contribute to market growth.
However, the high cost associated with
product research and development raises the cost of the final product and
associated treatment, which is expected to stymie the growth of the immune
checkpoint inhibitors market. Furthermore, the high cost of immune checkpoint
inhibitors has resulted in regulatory price caps. The regulatory price caps on
immune checkpoint inhibitors are also expected to stymie the market's growth.
Bristol-Myers Squibb Company, Astra Zeneca
plc, Merck & Co., Pfizer, Inc., F. Hoffmann-La Roche AG, Incyte
Corporation, NewLink Genetics Corporation, Seattle Genetics, Inc., Celldex
Therapeutics, GlaxoSmithKline plc, and Innate Pharma S.A. are among the major
players involved in immune checkpoint inhibitor research and development.
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